Understanding Domperidone: Uses, Side Effects, and Mechanism of Action

Article Plan⁚ Understanding Domperidone

Domperidone Uses and Dosage
Domperidone Side Effects⁚ What to Expect
Domperidone for Nausea and Vomiting Relief
Domperidone and Breast Milk Production
Domperidone⁚ Mechanism of Action Explained
Domperidone Precautions and Considerations

Domperidone Uses and Dosage

Domperidone is commonly used to treat nausea and vomiting.​ The typical adult dose is 10mg taken up to three times a day.​ It’s important to follow the doctor’s instructions. For children, the dose may vary based on weight.​ Domperidone should be taken 15-30 minutes before meals for best results.

Domperidone Side Effects⁚ What to Expect

Common side effects of domperidone include headache, dry mouth, and dizziness.​ More serious side effects may include irregular heartbeat or allergic reactions.​ It’s important to seek medical help if you experience severe side effects.​ Domperidone may interact with other medications, so inform your doctor about all the medicines you are taking.​

Domperidone for Nausea and Vomiting Relief

Domperidone is used to relieve symptoms of nausea and vomiting. It works by blocking dopamine receptors in the brain and gut, helping to regulate stomach contractions and prevent vomiting.​ This medication can be particularly effective for individuals with conditions like gastroparesis, where stomach emptying is delayed.​

Domperidone and Breast Milk Production

Domperidone is sometimes prescribed off-label to help increase milk supply in breastfeeding mothers. It works by blocking dopamine receptors, leading to increased prolactin levels, which in turn promotes milk production.​ When taking domperidone for this purpose, it’s essential to follow the recommended dosage and consult with a healthcare provider.

Domperidone⁚ Mechanism of Action Explained

Domperidone functions by antagonizing dopamine receptors, particularly the D2 receptors.​ By blocking these receptors in the gut and brain, domperidone enhances the motility of the upper gastrointestinal tract and inhibits nausea and vomiting.​ This mechanism of action makes it effective in treating conditions that involve delayed gastric emptying or disrupted gastrointestinal motility.​

Domperidone Precautions and Considerations

Before taking domperidone, inform your healthcare provider about any medical conditions you have, especially heart issues.​ Domperidone may cause cardiac arrhythmias in some individuals.​ It’s important to avoid alcohol while using domperidone as it can exacerbate certain side effects. Pregnant individuals or those with kidney problems should consult a doctor before starting domperidone.

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